This course explores the interface between traditional Indian Knowledge Systems (IKS) and modern life sciences, highlighting how ancient wisdom contributes to contemporary understanding of health, environment, and sustainable living. It introduces the philosophical foundations of Indian sciences through Ayurveda, Yoga, Siddha, and Unani, focusing on concepts of health, disease prevention, nutrition, and holistic well-being. The curriculum emphasizes indigenous practices in biodiversity conservation, agriculture, and ethnomedicine, while drawing parallels with modern biology, ecology, and biotechnology. Students gain insights into traditional food systems, medicinal plants, and lifestyle practices, examining their relevance for modern challenges such as stress, chronic diseases, and environmental sustainability. Through case studies, comparative analysis, and integrative perspectives, the course fosters appreciation of India’s scientific heritage and equips learners with knowledge to blend traditional wisdom with modern scientific approaches for innovation and societal benefit.